Nick Mitchell’s Ultimate Performance

The following abstract from the Journal of Endocrinology highlights the importance of growth hormone and it’s positive impact upon body composition.  Here at Ultimate Performance we make sure all our clients growth hormone levels are optimised.  This can be done via intelligent nutrition, GH inducing training protocols and the use of supplements such as Alpha GPC. Some people wonder why our clients get such consistently stellar fat loss results and an emphasis on natural growth hormone production is definitely one of our so-called “secrets”.

Abstract: The anabolic actions of GH in GH-deficient adults and children are well documented. Replacement with GH in such individuals promotes protein synthesis and reduces irreversible loss of protein through oxidation. Although GH is known to be self-administered by athletes, its protein metabolic effects in this context are unknown. This study was designed to determine whether 4 wk of high dose recombinant human GH (r-hGH) administration altered whole body leucine kinetics in endurance-trained athletes at rest and during and after 30 min of exercise at 60% of maximal oxygen uptake. Eleven endurance- trained male athletes were studied, six randomized to receive r-hGH (0.067 mg/kg
d), and five to receive placebo.
Whole body leucine turnover was measured at rest and during and after exercise, using a 5-h primed constant infusion of 1-[13C]leucine, from which rates of leucine appearance (an index of protein breakdown), leucine oxidation, and nonoxidative leucine disposal (an index of protein synthesis) were estimated. Under resting conditions, r-hGH administration increased rate of leucine appearance and nonoxidative leucine disposal, and reduced leucine oxidation (P < 0.01). This effect was apparent after 1 wk, and was accentuated after 4 wk, of r-hGH administration (P < 0.05). During and after exercise, GH attenuated the exercise-induced increase in leucine oxidation (P < 0.05). There were no changes observed in placebo-treated subjects compared with the baseline study. We conclude that GH administration to endurance-trained male athletes has a net anabolic effect on whole body protein metabolism at rest and during and after exercise. (J Clin Endocrinol Metab 88: 5221–5226, 2003)